The nicotine inhaler and the mouth/nasal spray are the two less-common NRT forms. They fill specific niches that gum and lozenges cannot.
The mouth or nasal spray
- How it works: one or two sprays into the mouth or nose deliver nicotine that absorbs through the mucosa.
- Onset: 5-10 minutes — the fastest NRT.
- Best for: sudden, hard cravings that gum cannot catch in time.
- Availability: OTC in the UK (Nicorette QuickMist); OTC or prescription in the US.
- Side effects: brief throat or nose irritation in the first week; usually settles.
The inhaler
- How it works: a plastic mouthpiece holds a cartridge; you draw on it, and nicotine absorbs in the mouth.
- Onset: ~20 minutes.
- Best for: users who miss the hand-to-mouth ritual as much as the nicotine.
- Availability: prescription in the US and UK.
- Note: not a vape substitute — nicotine goes to the mouth, not the lungs.
When to choose spray or inhaler over gum
- Cravings come on faster than 10-15 minutes (spray).
- You cannot use gum/lozenge (dentures, jaw problems, acid reflux).
- The hand-to-mouth ritual is the hardest part (inhaler).
- You are combining with a patch and need a fast rescue form.
Combining
Both pair well with a patch as part of combination NRT.



